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Innovate UK awards major grant to develop Rheumatoid Arthritis Flare Profiler

first_imgReviewed by James Ives, M.Psych. (Editor)Jan 30 2019A partnership between the healthtech company Living With, the Royal United Hospitals Bath NHS Foundation Trust (RUH), and the University of Bath has been awarded a major grant to develop a Rheumatoid Arthritis Flare Profiler.The award, from Innovate UK, will allow rheumatoid arthritis patients to use new methods capturing key disease activity data from smartphones, which will support clinicians to be able to classify and optimize care pathways.Living With is developing the Flare Profiler in partnership with the RUH Trust’s Royal National Hospital for Rheumatic Diseases (RNHRD), which is the internationally leading centre of excellence for rheumatic conditions, and University of Bath’s Centre for the Analysis of Motion, Entertainment Research and Applications (CAMERA), a leader in developing and evaluating new digital technologies such as the use of video, sound and motion for clinical application.”We’re thrilled to have won an Innovate UK grant,’ says Living With’s CEO Chris Robson. “This will transform the way patients with rheumatoid arthritis can be monitored intelligently between appointments and hopefully help the NHS reduce the cost of treating patients with RA. It also adds a transformational new capability to our existing Living With Rheumatoid Arthritis product.”Related StoriesFirst safe, reliable, noninvasive way to monitor rheumatoid arthritisResearchers develop NO-scavenging hydrogel for treatment of rheumatoid arthritisResearchers identify new molecular mechanism causing rheumatoid arthritisJane Carter, Research & Development Manager at the RNHRD, said: “The Trust has an established international reputation for research and expertise in rheumatology. We are always looking at ways to further improve the care and treatments we can offer patients. Using the latest technology and artificial intelligence is an exciting development. We are very excited to be part of this innovative project.”CAMERA was created to help further and transfer the knowledge developed within computer science, often targeting technology developed for the entertainment industries, to other sectors such as healthcare.CAMERA Director, Professor Darren Cosker, says “This is a great project. Being able to take some of the computer vision techniques we developed for hand tracking for animation and transferring it into a condition monitoring platform that can operate in a person’s home is a very positive use of technology and exactly the kind of work we should all be doing.”The Flare Profiler will test a unique range of patient data sources including video and thermal imaging technology. The project will then analyze patient data using cutting edge artificial intelligence (AI) and machine-learning technology to group patient disease activity patterns and identify the most effective treatment pathways for them.The aim of the Flare Profiler is to demonstrate how better monitoring can provide earlier detection of issues, allow earlier clinical intervention and over time reduce need for costly acute treatments. It also aims to reduce the stress and need for patients to travel to hospital during treatment for specialist tests.Source: https://www.bath.ac.uk/announcements/smartphone-technology-will-use-ai-to-help-arthritis-patients-manage-their-flare-ups/last_img read more

Visual discovery startup Pinterest files for IPO Update

first_img The San Francisco-based bulletin board that connects people with interests including food, fashion, travel and lifestyle said it would trade under the symbol PINS on the New York Stock Exchange.”Pinterest is where more than 250 million people around the world go to get inspiration for their lives,” the company said in its filing with the Securities and Exchange Commission, which is expected to seek a valuation of around $12 billion.”They come to discover ideas for just about anything you can imagine: daily activities like cooking dinner or deciding what to wear, major commitments like remodeling a house or training for a marathon, ongoing passions like fly fishing or fashion and milestone events like planning a wedding or a dream vacation.”Documents for the initial public offering showed Pinterest lost $63 million in 2018 on revenue of $755.9 million. That compared with a loss of $130.0 million on $473 million in 2017 revenue.Launched in 2010, Pinterest brings in money from its role in online shopping and from advertising.It becomes the latest of the richly valued tech startups worth more than $1 billion, sometimes called “unicorns,” to hit Wall Street. Ride-hailing giant Lyft is expected to begin trading next week and rival Uber is likely to announce terms of its IPO soon.Details of the Pinterest offering were absent, with a temporary placeholder sum of $100 million to be raised, an amount likely to rise substantially.Like several other startups, Pinterest will use a dual-class share structure that enables the founders, including chief executive Ben Silbermann, to retain control.The research firm eMarketer expects Pinterest’s global ad revenues to hit $1 billion this year, making up just 0.3 percent of the total digital ad spend.Millennials and momsPinterest boasts having become a hit with millennials and women who wield buying clout in homes, winning their attention with virtual bulletin boards that they decorate with pictures showcasing interests in anything from food to sports, fashion or travel.Pinterest went on to weave in advertising and ways to buy items shown in posts, but said in the SEC filing that “substantially all” of its revenue comes from ads.Risk factors cited by Pinterest included competitors mimicking its products well enough to lure away users.Facebook-owned Instagram this week ramped up its challenge to Pinterest, moving into potentially lucrative e-commerce by adding an option to buy products shown off in posts by selected brands.A new “checkout” button for instant purchasing launched in a beta version of the app in the US with a limited number of businesses, according to the popular image-centric messaging service.”When you find a product you love, you can now buy it without leaving the app,” the Silicon Valley based division said in an online post.Previously, people inspired to buy products featured in Instagram posts had to follow links to outside online shopping sites.Pinterest also warned potential investors that while a Comscore study indicated that its US audience is 43 percent of internet users, including about 80 percent of adult women with children, it will need to penetrate other demographics such as men and international users for growth.Laws regarding data privacy or removing content could also hamper the online bulletin board, according to the filing. Pinterest, the online visual discovery platform with an estimated 250 million users, filed for a public share offering Friday, the latest of the big venture-backed startups to hit Wall Street. Pinterest CEO Ben Silbermann is seen during the TechCrunch Disrupt SF 2017 conference Pinterest files confidentially for stock listing: report This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.center_img © 2019 AFP Explore further Citation: Visual discovery startup Pinterest files for IPO (Update) (2019, March 22) retrieved 17 July 2019 from https://phys.org/news/2019-03-digital-scrapbooking-site-pinterest-ipo.htmllast_img read more

Transforming the art industry with Blockchain

first_img Citation: Transforming the art industry with Blockchain (2019, April 10) retrieved 17 July 2019 from https://phys.org/news/2019-04-art-industry-blockchain.html This was not an isolated case. In the past decade, many other prestigious London auction houses and New York galleries have also been caught out selling paintings, purportedly by artists ranging from old masters to modern abstract expressionists, which have been shown to be fakes.Swinburne researchers have developed an electronic system that promises to make life more difficult for art forgers. Professor Yang Xiang, Dean of the Digital Research Innovation Capability Platform, and his colleagues in the Data Science Research Institute, are using the same cyber security approach used by Bitcoin to guarantee the provenance and authenticity of works of art.The system should not only improve logistics for the art trade—an $82 billion dollar annual global market—but provide additional benefits to artists, such as ongoing royalties.Swinburne and its partner, Melbourne-based start-up ArtChain Global, announced the secure art-trading platform in 2018. “We anticipate this new system will be a game-changing technology,” Xiang says. “The Swinburne-developed secure digital technology underpinning the platform has applications far beyond the art world, potentially ranging from logistics to healthcare,” he adds.ArtChain enters the marketXiang’s partnership with ArtChain Global came about in late 2017, when the Melbourne-based group approached the cyber security researcher to ask if Swinburne had any capabilities with a computer technology called blockchain. “We have a number of researchers working on R&D blockchain projects, so it was a perfect fit,” Xiang says.Blockchain is best known in the context of Bitcoin and its competitor online virtual currencies. Blockchain creates the secure environment within which these ‘cryptocurrencies’ can be stored and traded. “Cryptocurrencies are the first real-world application of blockchain technology,” Xiang says.”To describe how blockchain works, I like to use a marriage ceremony as an example,” Xiang says. On the big day, friends and family all witness the event and can each verify that the ceremony took place. Q&A: What is bitcoin? Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Credit: CC0 Public Domain Provided by Swinburne University of Technology Sometimes an art forgery is so sophisticated, it fools even the experts. For example, in 2011, Sotheby’s brokered a deal for a darkly coloured gentleman’s portrait said to be by 17th century painter Frans Hals the Elder. The buyer paid roughly AU$15 million (US$10.9 million). In 2016, amid a string of similar scandals, this work was discovered to be made partially of synthetic paint, making its supposed provenance impossible. In the case of a cryptocurrency transaction, a distributed network of invited computers act as the witnesses, each recording that an exchange of funds took place. Just as everyone invited to the wedding remembers the event, the computers all hold an identical copy of the transaction record. If anybody tried to fraudulently manipulate a cryptocurrency record, the doctored copy would no longer match all the other computers’ version and the change would be rejected. “Bitcoin is the first application that shows blockchain’s potential,” says Xiang. But the same idea could underpin almost any type of transaction, he says.Including the trade of art. “Although there are so many high-value transactions, one of the key problems in this industry is the authenticity of the artworks and collectables,” he says. Developing an art-trading platform based on blockchain would eliminate that concern. Using blockchain would be akin to having multiple witnesses on hand to observe the artist selling a piece to a dealer or collector, and then witnessing each onward sale of the piece.Technologically, adapting blockchain code for a new application is not too difficult, as there are several open source blockchain platforms available for use, says Xiang. The biggest challenge has been developing protocols to robustly connect the physical artwork to its digital blockchain record. The team has applied cutting-edge electronic technologies to overcome this challenge, Xiang explains.The first level of security comes from attaching to the object a smart, internet-enabled electronic tag, connecting the artwork to the internet of things (IoT). These tags, which give the artwork a unique online identify, can also be integrated with GPS tracking modules, so its physical location is always known.As a further security measure, the team has developed an artificial intelligence (AI) program that analyses high-resolution camera images of the real artwork. “If there is a fake, very minor features not recognisable by human eyes can be detected by AI,” Xiang says. AI, which is based on deep learning algorithms, was trained to spot fakes by allowing it to analyse a huge library of images. Attributes such as colour saturation, brightness and depth are all analysed to detect minor differences between the real version and the copy. The system is already working quite well in the lab, says Xiang. Real-world testing began in 2018.The art-trading platform will integrate all these new technologies into a single interface. “We have developed a combined system that utilises AI and IoT, plus the blockchain,” Xiang says. “So the whole system involves multiple new technologies, all done at Swinburne.”Ongoing royaltiesJohn Young, a Melbourne artist and studio owner, has been consulting for ArtChain Global as the platform was developed. “I am very optimistic about its possibilities,” says Young. “There are several areas where this is clearly a very good thing.” Not least, of course, is confirming the authenticity of an artwork.Although forged work, claimed to be painted by figures such as Jackson Pollock, tend to grab headlines, these high-profile cases are the tip of the iceberg when it comes to art copying. A more prevalent threat for today’s working artists is having online images of their artworks copied and used without permission, attribution or payment.”I have had people lift work from my website, then blow it up to full size and use it as a shop window display,” Young says.Registering a work on ArtChain would be a safeguard, providing a timeline and proving that Young was the creator of the work.Aside from its security credentials, the other key feature is the way the blockchain record grows over time. Each time an object is traded—be it a Bitcoin or a painting—a new line item (or ‘block’) is added to the end of the existing record file. The record itself therefore serves as a chronological history of the object’s ownership and its provenance.”For the art market, provenance is very important,” Young says. “A work held in a collection for 50 years is sometimes seen as more valuable than a piece that has been continually traded on the secondary market.”The growing blockchain record has other potential advantages for the art trade. It allows for royalty payments for the artist for each onward sale of their work. Items sold by artists early in their career can significantly increase in value over time as the artist makes a name. “Traditionally the artist cannot get any benefit from that, says Xiang. “In the blockchain platform, we embedded a new royalty system. Because blockchain cannot be manipulated or changed by third parties, the artist can collect the royalties many years later,” he says.Artists will need to be educated about blockchain based art transactions before they are likely to embrace it, Young says. “Like any start-up technology, users need some convincing in terms of trust.” But Xiang says the reception to the system so far has been positive among artists.ArtChain also plans to expand into Asian countries.From art to antimalarialsFor Xiang and his team, the blockchain-based art-trading platform is just the beginning of their work in this area. “The fundamental technology is applicable to many other areas, in particular in supply chains,” says Xiang.Their system for combining, AI, IoT and blockchain could be readily adapted for the trade of other collectable items, such as jewellery.The technology could also become an indispensable tool in stemming the expanding trade in counterfeit medicines.Fake versions of antimalarial drugs, containing little or no active ingredient, are of particular concern, according to the World Health Organization, which found that substandard and counterfeit medicines may cause up to 116,000 malaria deaths each year in sub-Saharan Africa alone.Developing countries are particularly vulnerable to fake drug imports, as they often lack the resources to detect the crime. But, even in tightly regulated countries such as Australia, a small number of counterfeit medicines can sometimes be slipped into the healthcare system.The same blockchain-IoT technology Xiang has developed to record the authenticity and provenance of artworks could be used to secure the pharmaceutical supply chain, providing traceability of each drug carton back to the original manufacturer. A blockchain-based platform like this could augment efforts to control the problem by regulators and pharmaceutical companies, which already includes making packaging harder to fake.”In the next few months we will have connections with other industries, particularly in the area of healthcare, education, transportation and logistics,” Xiang says.last_img read more

Yahoo to pay 1175M in latest settlement of massive breach

first_img The deal revises an earlier agreement struck last October, only to be rejected by U.S. District Court Judge Lucy Koh in San Jose, California. The value of that settlement had been pegged at $50 million, but Koh questioned the calculations.A more detailed breakdown used in the revised settlement drove up the estimated cost. The money will be paid by Yahoo’s current owner, Verizon, and Altaba, a holdover from Yahoo’s past that still owns a stake in Chinese internet company Alibaba Group worth billions of dollars.If approved, the settlement will become part of the financial fallout from digital burglaries that stole personal information from about 3 billion Yahoo accounts in 2013 and 2014—believed to be the biggest data breach ever.And now the $117.5 million settlement could become largest amount ever doled out for a data breach, a recurring problem in an increasingly digitally driven world. It eclipses a $115 million settlement that Koh approved last year to cover 79 million people who had personal information stolen in a 2015 breach at health insurer Anthem Inc.Yahoo didn’t begin to disclose the extent of its security breakdown until 2016 amid an FBI investigation that eventually linked some of the hacking to Russia . The revelations brought a mortifying end to the reign of Yahoo CEO Marissa Mayer, eventually prompting the company to reduce its selling price to Verizon by $350 million.Verizon has since written off much of the nearly $4.5 billion price for the Yahoo acquisition in sign of the eroding value of that business.Lawyers representing the Yahoo accountholders estimate about 194 million people in U.S. and Israel will be eligible to make claims, according to court documents. Those people collectively may have had about 896 million of the Yahoo accounts hit in the break-ins.The biggest piece of the revised Yahoo settlement disclosed in documents filed Tuesday consists of the free credit-monitoring services that will be offered to everyone covered by the deal to protect them from identity theft and other potential problems. The service from AllClear usually costs $14.95 per month, or $359 for two years. People who already have a credit-monitoring service will be eligible for cash payments instead.Yahoo accountholders who paid anywhere for $20 to $50 annually for premium email accounts will be eligible for refunds of up to 25%. People who had to spend time protecting their identities or dealing with other issues caused by the breach can be seek to be paid at a rate of $25 per hour for up to 15 hours.The settlement will also pay up to $32.5 million in fees and other expenses to the lawyers representing Yahoo accountholders, down from the $37.5 million sought in the earlier agreement—another sticking point for Koh.A hearing on the revised settlement is scheduled for June 27. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2019 The Associated Press. All rights reserved. Explore further In this Dec. 15, 2016, file photo, the Yahoo logo appears on a smartphone in Frankfurt, Germany. Nearly 200 million people who had sensitive information snatched from their Yahoo accounts will receive two years of free credit-monitoring services and other potential restitution in a legal settlement valued at $117.5 million. The deal disclosed in documents filed Tuesday, April 9, 2019, revises an earlier agreement struck last October, only to be rejected by U.S. District Court Judge Lucy Koh in San Jose. (AP Photo/Michael Probst, File)center_img Yahoo to pay $50M, other costs for massive security breach Citation: Yahoo to pay $117.5M in latest settlement of massive breach (2019, April 10) retrieved 17 July 2019 from https://phys.org/news/2019-04-yahoo-1175m-latest-settlement-massive.html Nearly 200 million people who had sensitive information snatched from their Yahoo accounts will receive two years of free credit-monitoring services and other potential restitution in a legal settlement valued at $117.5 million.last_img read more

Lagos a rare isotop

Lagos, a rare isotope of carbon that enabled Beller’s team to trace the fate of the compound as it reacted. "Impeachment is a punishment.

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224 kmh (761 mph) o

224 km/h (761 mph). on other occasions the North Korean cheerleaders have described as weirdly detached from whats going on around them – ignoring a wedding proposal on the arenas video board to carry on singing.000 people Turkey has arrested in security sweeps in recent days. did not say whether they will cut Mar-Vell out of the story altogether.

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720 (One Billion Eight Hundred and Forty Million, seeking a declaration that all investigations against them by law enforcement agencies had been concluded. but instead continue to maintain proper vigilance and enjoy all that democracy offers. does it really matter whether the man with the cleaver had a mental illness, Aug."That hasn’t been a problem for me per se. read more